In this study, surface and radiosonde data from staffed Antarctic observation stations are compared tooutput from five reanalyses [Climate Forecast System Reanalysis (CFSR), 40-yr ECMWF Re-Analysis(ERA-40), ECMWF Interim Re-Analysis (ERA-Interim), Japanese 25-year Reanalysis (JRA-25), and Modern Era Retrospective-Analysis for Research and Applications (MERRA)] over three decades spanning 1979–2008. Bias and year-to-year correlation between the reanalyses and observations are assessed for four variables: mean sea level pressure (MSLP), near-surface air temperature (Ts), 500-hPa geopotential height (H500), and 500-hPa temperature (T500).It was found that CFSR andMERRAare of a sufficiently high resolution for the height of the orography tobe accurately reproduced at coastal observation stations. Progressively larger negative Ts biases at thesecoastal stations are apparent for reanalyses in order of decreasing resolution. However, orography height biascannot explain large winter warm biases in CFSR, JRA-25, andMERRA(11.18, 10.28, and 7.98C, respectively)at Amundsen–Scott and Vostok, which have been linked to problems with representing the surface energybalance. Linear trends in the annual-mean T500 andH500 averaged over Antarctica as a whole were found to be mostreliable in CFSR, ERA-Interim, and MERRA, none of which show significant trends over the period 1979–2008. In contrast JRA-25 shows significant negative trends over 1979–2008 and ERA-40 gives significantpositive trends during the 1980s (evident in both T500 andH500). Comparison to observations indicates that thepositive trend in ERA-40 is spurious. At the smaller spatial scale of individual stations all five reanalyses have some spurious trends. However, ERA-Interim was found to be the most reliable for MSLP andH500 trends atstation locations.